Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | CASR | P41180 | 4/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | GNRHR | P30968 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL115291 | 0.88 | TP53 (0.42) | TP53KDM4EKMT2AMAPTPOLB | |
| SCHEMBL115268 | 0.88 | KDM4E (0.35) | TP53CASRKDM4EHSD17B10MCL1 | |
| SCHEMBL115273 | 0.85 | BRD4 (0.35) | CASRKDM4EHSD17B10MCL1KDM5A | |
| SCHEMBL115317 | 0.83 | KDM5A (0.33) | TP53CASRKDM4EHSD17B10KDM5A | |
| SCHEMBL115110 | 0.76 | ADORA2B (0.41) | TP53KDM4EKMT2AMAPTPOLB | |
| SCHEMBL115043 | 0.76 | ERCC1 (0.39) | TP53CASRKDM4EHSD17B10GNRHR | |
| SCHEMBL114970 | 0.74 | CASR (0.34) | CASRNR1I2KMT2AGNRHR | |
| SCHEMBL115161 | 0.74 | HEXA (0.36) | CASRNR1I2KDM4EHSD17B10MCL1 | |
| SCHEMBL115144 | 0.72 | CASR (0.38) | CASRNR1I2GNRHR | |
| SCHEMBL116013 | 0.71 | GAA (0.42) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058893-A1 | HERBICIDALLY ACTIVE KETOSULTAMS AND DIKETOPYRIDINES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058893-A1 | HERBICIDALLY ACTIVE KETOSULTAMS AND DIKETOPYRIDINES | KHK, KCNA1, KCNA2 | TP53 4438/4885CASR 4298/4885NR1I2 2192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.