Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 6/20 | 0.34 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GNRHR | P30968 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.30 |
| ▸ | GHSR | Q92847 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL115096 | 0.86 | KDM4E (0.36) | CASRBRD4KCNH2GRM1 | |
| SCHEMBL115100 | 0.84 | METAP2 (0.40) | ESR1ESR2 | |
| SCHEMBL115943 | 0.82 | CASR (0.34) | CASRNR1I2ELANEKMT2AGNRHR | |
| SCHEMBL114962 | 0.82 | SMN1; SMN2 (0.34) | CASRBRD4KCNH2GRM1ESR1 | |
| SCHEMBL115067 | 0.81 | BRD4 (0.40) | CASRELANEKMT2ABRD4KCNH2 | |
| SCHEMBL115043 | 0.80 | ERCC1 (0.39) | CASRERCC5FEN1ELANEGNRHR | |
| SCHEMBL115145 | 0.79 | CASR (0.33) | CASRNR1I2ELANEGNRHRBRD4 | |
| SCHEMBL113677 | 0.78 | KCNA3 (0.32) | CASRNR1I2ELANEKMT2AGNRHR | |
| SCHEMBL115291 | 0.76 | TP53 (0.42) | KMT2A | |
| SCHEMBL115021 | 0.76 | CASR (0.33) | CASRNR1I2ELANEKMT2AGNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058893-A1 | HERBICIDALLY ACTIVE KETOSULTAMS AND DIKETOPYRIDINES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058893-A1 | HERBICIDALLY ACTIVE KETOSULTAMS AND DIKETOPYRIDINES | KHK, KCNA1, KCNA2 | CASR 4298/4885ERCC5 4625/4885FEN1 3630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.