Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11387518 | 0.95 | RAB9A (0.49) | RAB9ANPC1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11379786 | 0.84 | ALDH1A1 (0.52) | RAB9ANPC1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11383830 | 0.82 | ALDH1A1 (0.50) | RAB9ANPC1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11379351 | 0.82 | ALDH1A1 (0.49) | RAB9ANPC1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11376381 | 0.80 | ALDH1A1 (0.47) | RAB9ANPC1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11379612 | 0.79 | RIPK1 (0.34) | RIPK1 | |
| SCHEMBL11379615 | 0.79 | RIPK1 (0.34) | RIPK1 | |
| SCHEMBL11383035 | 0.77 | S1PR1 (0.33) | RAB9ANPC1HTTRIPK1 | |
| SCHEMBL4506446 | 0.76 | ALDH1A1 (0.68) | RAB9ANPC1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11382132 | 0.75 | ALDH1A1 (0.48) | RAB9ANPC1ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243674-A | HYPOTENSIVE AGENTS; ANALGESICS; ANTISECRETORY AGENTS; ANTIBODY INHIBITORS, AND TRANQUILIZERS | PFIZER INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4143139-A | ANALGESICS, HYPOTENSIVES, IMMUNOSUPPRESSANTS, TRANQUILIZERS, ANTISECRETORY, ANTI-ANXIETY | PFIZER INC. (US) | 1979-03-06 | — | — | US | disclosed |