Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 1/20 | 0.56 |
| ▸ | PDE5A | O76074 | 17/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PDE2A | O00408 | 1/20 | 0.45 |
| ▸ | PDE6D | O43924 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | PDE9A | O76083 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PDE6A | P16499 | 1/20 | 0.45 |
| ▸ | PDE6G | P18545 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE6B | P35913 | 1/20 | 0.45 |
| ▸ | PDE6C | P51160 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11378233 | 0.91 | GUSB (0.55) | GUSBPDE5AKDM4EALDH1A1HPGD | |
| SCHEMBL11380722 | 0.90 | PDE5A (0.59) | GUSBPDE5AKDM4EALDH1A1HPGD | |
| SCHEMBL11375840 | 0.88 | ALDH1A1 (0.58) | GUSBPDE5AKDM4EALDH1A1HPGD | |
| SCHEMBL11375259 | 0.87 | PDE5A (0.58) | GUSBPDE5AKDM4EALDH1A1HPGD | |
| SCHEMBL11374270 | 0.85 | ALDH1A1 (0.55) | GUSBPDE5AKDM4EALDH1A1HPGD | |
| SCHEMBL11383679 | 0.85 | PDE5A (0.66) | GUSBPDE5AKDM4EALDH1A1HPGD | |
| SCHEMBL11384695 | 0.83 | GUSB (0.71) | GUSBPDE5AMEN1MAPTPDE1A | |
| SCHEMBL11374673 | 0.82 | GUSB (0.58) | GUSBPDE5AKDM4EALDH1A1HPGD | |
| SCHEMBL11553644 | 0.82 | ALDH1A1 (0.53) | GUSBPDE5AKDM4EALDH1A1HPGD | |
| SCHEMBL11550624 | 0.81 | KDM4E (0.54) | GUSBPDE5AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | disclosed |
| EP-0020883-A1 | A process for preparing 3-beta-amino-4-beta-substituted 2-azetidinones and 3-(2,2-dihalogenovinyl)-imino-4-beta-substituted 2-azetidinone and 3-beta-(2,2-dihalogenovinyl)-amino-4-beta-substituted 2-azetidinone intermediates | SHIONOGI & CO., LTD. (JP) | 1981-01-07 | — | — | EP | disclosed |