Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 12/20 | 0.48 |
| ▸ | PDE4A | P27815 | 4/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.47 |
| ▸ | GUSB | P08236 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11380722 | 0.89 | PDE5A (0.59) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11375259 | 0.86 | PDE5A (0.58) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11374823 | 0.85 | L3MBTL1 (0.49) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11383679 | 0.83 | PDE5A (0.66) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11383000 | 0.82 | PDE5A (0.44) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11384809 | 0.79 | GUSB (0.56) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11384695 | 0.79 | GUSB (0.71) | PDE5AGUSBTP53NPC1POLB | |
| SCHEMBL11374673 | 0.79 | GUSB (0.58) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11375179 | 0.77 | PDE5A (0.45) | PDE5AGUSBTP53NPC1POLB | |
| SCHEMBL11381831 | 0.77 | PDE5A (0.46) | PDE5AGUSBTP53NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | claimed |
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | disclosed |