Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11381411 | 1.00 | RIPK1 (0.32) | RIPK1L3MBTL1MAOB | |
| SCHEMBL11372932 | 0.88 | RIPK1 (0.32) | RIPK1 | |
| SCHEMBL11372935 | 0.88 | RIPK1 (0.32) | RIPK1 | |
| SCHEMBL11379705 | 0.86 | — | — | |
| SCHEMBL11379703 | 0.86 | — | — | |
| SCHEMBL11378765 | 0.85 | TRPA1 (0.34) | — | |
| SCHEMBL11378760 | 0.85 | TRPA1 (0.34) | — | |
| SCHEMBL11379615 | 0.81 | RIPK1 (0.34) | RIPK1 | |
| SCHEMBL11379612 | 0.81 | RIPK1 (0.34) | RIPK1 | |
| SCHEMBL11377605 | 0.80 | GPR84 (0.34) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243674-A | HYPOTENSIVE AGENTS; ANALGESICS; ANTISECRETORY AGENTS; ANTIBODY INHIBITORS, AND TRANQUILIZERS | PFIZER INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4143139-A | ANALGESICS, HYPOTENSIVES, IMMUNOSUPPRESSANTS, TRANQUILIZERS, ANTISECRETORY, ANTI-ANXIETY | PFIZER INC. (US) | 1979-03-06 | — | — | US | disclosed |