Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11378327 | 0.89 | KDM4E (0.44) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL25386200 | 0.85 | ALDH1A1 (0.52) | KDM4EALDH1A1HPGDGAAMAPT | |
| Hydrochloric Acid SCHEMBL8472028 | 0.82 | HSD17B10 (0.46) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL11377261 | 0.80 | ALDH1A1 (0.49) | KDM4EALDH1A1MAPTTP53MAPK1 | |
| SCHEMBL10516254 | 0.80 | TSHR (0.49) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL11377802 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL11377800 | 0.79 | CA12 (0.64) | ALDH1A1GAAMAPTTSHRCA12 | |
| SCHEMBL10514703 | 0.77 | MAPK1 (0.48) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL11375452 | 0.76 | DPP4 (0.46) | ALDH1A1GAAMAPTSMN1; SMN2TDP1 | |
| SCHEMBL8469779 | 0.76 | ADRA1A (0.47) | KDM4EALDH1A1HPGDGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273773-A | IN COMBINATION WITH A DIURETIC | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-06-16 | — | — | US | disclosed |