Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11393959 | 0.89 | LMNA (0.67) | LMNAALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL11377362 | 0.88 | ALDH1A1 (0.67) | LMNAALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL11369368 | 0.87 | RXFP1 (0.50) | LMNAALDH1A1SMN1; SMN2HTTRXFP1 | |
| SCHEMBL11642713 | 0.85 | ALDH1A1 (0.53) | LMNAALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL11385764 | 0.83 | LMNA (0.65) | LMNAALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL11388773 | 0.83 | ALDH1A1 (0.51) | LMNAALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL11381445 | 0.82 | LMNA (0.64) | LMNAALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL11375460 | 0.82 | ALDH1A1 (0.63) | LMNAALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL11641263 | 0.81 | RXFP1 (0.58) | LMNAALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL11377101 | 0.81 | ALDH1A1 (0.51) | LMNAALDH1A1SMN1; SMN2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273930-A | INTERMEDIATES FOR THE 4-ALKOXY ANTIALLERGENS | SANDOZ, INC. (US) | 1981-06-16 | — | — | US | disclosed |
| US-4190659-A | ANTIALLERGENS, ANTIHISTAMINES | SANDOZ, INC. (US) | 1980-02-26 | — | — | US | disclosed |