Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 2/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11384637 | 1.00 | KMT2A (0.50) | KMT2ARAB9AMAPTADAM17ATM | |
| SCHEMBL11385539 | 0.91 | KMT2A (0.53) | KMT2ARAB9AMAPTADAM17ATM | |
| SCHEMBL11385542 | 0.91 | KMT2A (0.53) | KMT2ARAB9AMAPTADAM17ATM | |
| SCHEMBL9630054 | 0.84 | MAPT (0.52) | KMT2ARAB9AMAPTADAM17ATM | |
| SCHEMBL9630045 | 0.84 | MAPT (0.52) | KMT2ARAB9AMAPTADAM17ATM | |
| SCHEMBL10942540 | 0.83 | PTPN1 (0.50) | ACECTSLPTPN1 | |
| SCHEMBL10805856 | 0.83 | PTPN1 (0.50) | ACECTSLPTPN1 | |
| SCHEMBL20122460 | 0.79 | ACE (0.51) | KMT2ARAB9AMAPTADAM17ATM | |
| SCHEMBL20122473 | 0.78 | MAPT (0.46) | KMT2ARAB9AMAPTADAM17ATM | |
| SCHEMBL10667128 | 0.76 | ACE (0.47) | KMT2ARAB9AMEN1ACECTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4259508-A | MUCOLYTIC, EMOLLIENT | BLUM JEAN | 1981-03-31 | — | — | US | disclosed |