Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSPA5 | P11021 | 4/20 | 0.46 |
| ▸ | HSPA2 | P54652 | 2/20 | 0.46 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.46 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11385542 | 1.00 | KMT2A (0.53) | KMT2AMAPTADAM17ATMCTSL | |
| SCHEMBL11384632 | 0.91 | KMT2A (0.50) | KMT2AMAPTADAM17ATMCTSL | |
| SCHEMBL11384637 | 0.91 | KMT2A (0.50) | KMT2AMAPTADAM17ATMCTSL | |
| SCHEMBL9630054 | 0.88 | MAPT (0.52) | KMT2AMAPTADAM17ATMCTSL | |
| SCHEMBL9630045 | 0.88 | MAPT (0.52) | KMT2AMAPTADAM17ATMCTSL | |
| SCHEMBL20122460 | 0.82 | ACE (0.51) | KMT2AMAPTADAM17ATMCTSL | |
| SCHEMBL20122473 | 0.81 | MAPT (0.46) | KMT2AMAPTADAM17ATMCTSL | |
| SCHEMBL9705400 | 0.81 | RAB9A (0.54) | KMT2ACTSLRAB9AHPGDHDAC1 | |
| SCHEMBL11386076 | 0.81 | RAB9A (0.54) | KMT2ACTSLRAB9AHPGDHDAC1 | |
| SCHEMBL9705401 | 0.81 | RAB9A (0.54) | KMT2ACTSLRAB9AHPGDHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4259508-A | MUCOLYTIC, EMOLLIENT | BLUM JEAN | 1981-03-31 | — | — | US | disclosed |