Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 12/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 10/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | LYN | P07948 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726444 | 0.72 | PRKCQ (0.46) | PRKCQPRKCDTRPA1 | |
| SCHEMBL113504 | 0.70 | BRD4 (0.39) | PRKCQPRKCDDRD1TRPA1 | |
| SCHEMBL30326312 | 0.70 | MKNK1 (0.36) | PRKCQPRKCDDRD1LYNL3MBTL1 | |
| SCHEMBL7096071 | 0.68 | IMPDH2 (0.49) | PRKCQPRKCDTRPA1 | |
| SCHEMBL13075464 | 0.68 | BRD4 (0.39) | DRD1TRPA1 | |
| SCHEMBL1516621 | 0.68 | CSNK1D (0.50) | PRKCQPRKCDLYN | |
| SCHEMBL20282675 | 0.66 | POLB (0.54) | L3MBTL1 | |
| SCHEMBL10125110 | 0.66 | LRRK2 (0.58) | PRKCQPRKCD | |
| SCHEMBL10472465 | 0.65 | L3MBTL1 (0.42) | L3MBTL1 | |
| SCHEMBL1883357 | 0.62 | GRIA1 (0.51) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424843-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF CYCLIN DEPENDENT KINASES | Novartis AG (CH) | 2012-03-07 | — | — | EP | claimed |
| WO-2010125402-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF CYCLIN DEPENDENT KINASES | NOVARTIS AG (CH) | 2010-11-04 | — | — | WO | claimed |