Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 16/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 15/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.38 |
| ▸ | USP2 | O75604 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.37 |
| ▸ | CASP1 | P29466 | 7/20 | 0.37 |
| ▸ | CASP7 | P55210 | 7/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | GLA | P06280 | 3/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.37 |
| ▸ | HBB | P68871 | 2/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL115126 | 0.85 | PDE4B (0.38) | CYP1A2CYP3A4ALDH1A1CYP2C19HPGD | |
| SCHEMBL116200 | 0.85 | BRD4 (0.33) | ALDH1A1MAPK1TSHRADORA2BMAPT | |
| SCHEMBL113710 | 0.83 | BRD4 (0.38) | ALDH1A1KMT2AMAPTHPGD | |
| SCHEMBL115974 | 0.81 | METAP2 (0.42) | — | |
| SCHEMBL113626 | 0.81 | SMN1; SMN2 (0.34) | GLAADORA2B | |
| SCHEMBL115943 | 0.81 | CASR (0.34) | KMT2A | |
| SCHEMBL115242 | 0.74 | PDE5A (0.37) | CYP1A2ALDH1A1CYP2C19HSD17B10TSHR | |
| SCHEMBL115271 | 0.73 | KMT2A (0.35) | CYP1A2ALDH1A1CYP2C19HSD17B10CASP1 | |
| SCHEMBL12603544 | 0.72 | MAPT (0.39) | ALDH1A1USP2MEN1KMT2ATSHR | |
| SCHEMBL115259 | 0.70 | PDE5A (0.33) | CYP1A2ALDH1A1CYP2C19HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058893-A1 | HERBICIDALLY ACTIVE KETOSULTAMS AND DIKETOPYRIDINES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058893-A1 | HERBICIDALLY ACTIVE KETOSULTAMS AND DIKETOPYRIDINES | KHK, KCNA1, KCNA2 | CYP1A2 149/4885CYP3A4 408/4885ALDH1A1 274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.