Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | POLA1 | P09884 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11397306 | 0.80 | ALDH1A1 (0.39) | ALDH1A1LMNACYP3A4TDP1ACE2 | |
| SCHEMBL11804227 | 0.79 | CYP3A4 (0.47) | PPARGPPARAALDH1A1LMNACYP3A4 | |
| SCHEMBL11402166 | 0.78 | LMNA (0.44) | ALDH1A1LMNACYP3A4TDP1MAPK1 | |
| SCHEMBL11391703 | 0.77 | GPR52 (0.51) | ALDH1A1LMNACYP3A4MEN1MAPK1 | |
| SCHEMBL11402433 | 0.77 | MAPT (0.42) | PPARGTRPA1ALDH1A1FAAH | |
| SCHEMBL11394701 | 0.77 | MAPT (0.42) | PPARGTRPA1ALDH1A1FAAH | |
| SCHEMBL11402446 | 0.77 | MAPT (0.42) | PPARGTRPA1ALDH1A1FAAH | |
| SCHEMBL11407909 | 0.76 | HPGD (0.46) | PPARAALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL11862560 | 0.76 | ALDH1A1 (0.52) | ALDH1A1LMNACYP3A4TDP1KDM4E | |
| SCHEMBL11862556 | 0.76 | ALDH1A1 (0.52) | ALDH1A1LMNACYP3A4TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0026876-A1 | N-phenoxyalkylpiperidine derivatives, processes for their preparation and medicaments containing these compounds | Roche Diagnostics GmbH (DE) | 1981-04-15 | — | — | EP | disclosed |