Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11390814 | 0.86 | FBP1 (0.46) | FBP1RAB9AHSD17B10KDM4EMAPK1 | |
| SCHEMBL11390793 | 0.83 | FBP1 (0.44) | FBP1RAB9AHSD17B10KDM4EMAPK1 | |
| SCHEMBL11400234 | 0.81 | KDM4E (0.54) | FBP1RAB9AHSD17B10KDM4EMAPK1 | |
| SCHEMBL11393931 | 0.77 | FBP1 (0.51) | FBP1RAB9AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL11388406 | 0.74 | FBP1 (0.50) | FBP1KDM4EMAPK1ALDH1A1MEN1 | |
| SCHEMBL11397185 | 0.71 | CA1 (0.42) | FBP1KDM4EALDH1A1L3MBTL1HPGD | |
| SCHEMBL11396073 | 0.69 | FBP1 (0.47) | FBP1HSD17B10KDM4EMAPK1ALDH1A1 | |
| SCHEMBL14742913 | 0.68 | RAB9A (0.49) | RAB9AHSD17B10KDM4EMAPK1ALDH1A1 | |
| SCHEMBL4921514 | 0.67 | HDAC1 (0.73) | RAB9AHSD17B10KDM4EMAPK1PTPN1 | |
| SCHEMBL25262559 | 0.66 | RAB9A (0.79) | RAB9AKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4288449-A | DIURETICS | BASF AKTIENGESELLSCHAFT (DE) | 1981-09-08 | — | — | US | disclosed |