Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743107 | 0.89 | LMNA (0.49) | RAB9AKDM4EMAPK1HSD17B10NPSR1 | |
| SCHEMBL14743705 | 0.87 | MEN1 (0.51) | RAB9AKDM4EHDAC1HDAC8HDAC6 | |
| SCHEMBL14743993 | 0.86 | MAPK1 (0.56) | RAB9AKDM4EMAPK1L3MBTL1KCNMA1 | |
| SCHEMBL14743714 | 0.85 | MAPT (0.56) | RAB9AKDM4ENPSR1MAPTHPGD | |
| SCHEMBL14744278 | 0.84 | ALDH1A1 (0.57) | RAB9AKDM4EHDAC1MAPTHPGD | |
| SCHEMBL14743294 | 0.83 | POLB (0.55) | RAB9AMAPK1HDAC1HDAC8HDAC6 | |
| SCHEMBL14743980 | 0.82 | NPC1 (0.51) | RAB9AKDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL14744260 | 0.82 | SMN1; SMN2 (0.55) | RAB9AKDM4EMAPK1HPGDALDH1A1 | |
| SCHEMBL14743721 | 0.82 | ALDH1A1 (0.54) | KDM4EHSD17B10MAPTHPGDALDH1A1 | |
| SCHEMBL14743299 | 0.81 | ALDH1A1 (0.42) | RAB9AKDM4EHSD17B10L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | disclosed |