Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.36 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.35 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11395063 | 0.84 | MAPT (0.39) | KMT2AMEN1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL11392990 | 0.82 | PPARA (0.40) | KMT2APOLBMEN1HPGDRAB9A | |
| SCHEMBL11400055 | 0.81 | POLB (0.45) | POLBKDM4EPPARGPPARDGAA | |
| SCHEMBL11398878 | 0.79 | SLC6A2 (0.37) | TDP1 | |
| SCHEMBL11407909 | 0.76 | HPGD (0.46) | KMT2AMEN1HPGDSMN1; SMN2TDP1 | |
| SCHEMBL11394250 | 0.76 | MAPT (0.39) | POLBTSHRMAPTTDP1 | |
| SCHEMBL11395959 | 0.75 | AKT1 (0.46) | KMT2AHPGDRAB9AMAPTRECQL | |
| SCHEMBL11391703 | 0.74 | GPR52 (0.51) | KMT2AMEN1RAB9AMAPTL3MBTL1 | |
| SCHEMBL11395451 | 0.73 | FFAR1 (0.38) | KMT2AMEN1SMN1; SMN2MAPTTDP1 | |
| SCHEMBL11402166 | 0.73 | LMNA (0.44) | HPGDSMN1; SMN2RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0024282-A1 | Benzoyl derivatives, their preparation and their use as medicines | Dr. Karl Thomae GmbH (DE) | 1981-03-04 | — | — | EP | disclosed |