Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 2/20 | 0.36 |
| ▸ | ALPI | P09923 | 2/20 | 0.36 |
| ▸ | ALPG | P10696 | 2/20 | 0.36 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11407909 | 0.88 | HPGD (0.46) | PPARATDP1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL11392990 | 0.88 | PPARA (0.40) | MAPTPPARATDP1ALDH1A1LMNA | |
| SCHEMBL11400055 | 0.87 | POLB (0.45) | ALDH1A1 | |
| SCHEMBL11391897 | 0.84 | KMT2A (0.41) | MAPTPPARATDP1RAB9ASMN1; SMN2 | |
| SCHEMBL11394250 | 0.81 | MAPT (0.39) | MAPTTDP1ALDH1A1LMNACYP3A4 | |
| SCHEMBL11395959 | 0.81 | AKT1 (0.46) | MAPTPPARATDP1ALDH1A1LMNA | |
| SCHEMBL11391703 | 0.80 | GPR52 (0.51) | MAPTALDH1A1LMNACYP3A4KCNH3 | |
| SCHEMBL11395451 | 0.79 | FFAR1 (0.38) | MAPTTDP1ALDH1A1LMNACYP3A4 | |
| SCHEMBL11402166 | 0.79 | LMNA (0.44) | TDP1ALDH1A1LMNACYP3A4NPC1 | |
| SCHEMBL11402951 | 0.77 | LMNA (0.43) | ALDH1A1LMNAKCNH3HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243683-A | INSECTICIDES, MITICIDES | MAY & BAKER LIMITED (GB) | 1981-01-06 | — | — | US | claimed |
| US-4243683-A | INSECTICIDES, MITICIDES | MAY & BAKER LIMITED (GB) | 1981-01-06 | — | — | US | disclosed |