Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 3/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 3/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11378024 | 0.73 | PTGS2 (0.35) | PTGS2 | |
| SCHEMBL11529451 | 0.71 | PSEN1 (0.38) | PTGS2 | |
| Hydrochloric Acid SCHEMBL11379807 | 0.69 | SLC6A2 (0.45) | OPRK1 | |
| SCHEMBL11529076 | 0.69 | MT-CO2 (0.44) | PTGS2 | |
| SCHEMBL11377996 | 0.66 | TDP1 (0.41) | PTGS2 | |
| Isoprofen SCHEMBL287354 | 0.65 | PTGS2 (0.46) | OPRK1PTGS2 | |
| SCHEMBL11377617 | 0.64 | GRM7 (0.34) | OPRK1PTGS2 | |
| Isoprofen SCHEMBL11727169 | 0.64 | PTGS2 (0.45) | OPRK1PTGS2 | |
| Isoprofen SCHEMBL11377622 | 0.64 | PTGS2 (0.45) | OPRK1PTGS2 | |
| Isoprofen SCHEMBL11727175 | 0.63 | LMNA (0.42) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4271161-A | ANALGESICS | HEXACHIMIE (FR) | 1981-06-02 | — | — | US | disclosed |