Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11529076 | 0.86 | MT-CO2 (0.44) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL11378024 | 0.85 | PTGS2 (0.35) | TDP1L3MBTL1PTGS2TSHR | |
| SCHEMBL11377996 | 0.82 | TDP1 (0.41) | AKR1C3AKR1C2TDP1L3MBTL1PTGS2 | |
| Isoprofen SCHEMBL287354 | 0.81 | PTGS2 (0.46) | AKR1C3AKR1C2PTGS2MEN1KMT2A | |
| SCHEMBL11377617 | 0.80 | GRM7 (0.34) | AKR1C3AKR1C2TDP1L3MBTL1PTGS2 | |
| Isoprofen SCHEMBL11727169 | 0.80 | PTGS2 (0.45) | AKR1C3AKR1C2PTGS2MEN1KMT2A | |
| Isoprofen SCHEMBL11377622 | 0.80 | PTGS2 (0.45) | AKR1C3AKR1C2PTGS2MEN1KMT2A | |
| SCHEMBL28815680 | 0.78 | RAB9A (0.45) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Isoprofen SCHEMBL11727175 | 0.78 | LMNA (0.42) | PTGS2MEN1MAPTKMT2ATSHR | |
| SCHEMBL11527975 | 0.77 | SMN1; SMN2 (0.39) | L3MBTL1MEN1GAAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166131-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANTIARTHRITIC AGENT | HEXACHIMIE SOCIETE ANONYME (FR) | 1979-08-28 | — | — | US | disclosed |