Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 9/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11397533 | 0.89 | PTPN1 (0.52) | ALOX15MAOBGPR35PTPN1 | |
| SCHEMBL11394220 | 0.87 | ALOX15 (0.42) | ALOX15MAOBKMT2APTPN1MAOA | |
| SCHEMBL11567569 | 0.86 | ALOX15 (0.41) | ALOX15MAOBGPR35KMT2APTPN1 | |
| SCHEMBL11391248 | 0.83 | MAOB (0.56) | MAOBKMT2AMAOAALDH1A1 | |
| SCHEMBL11391983 | 0.81 | PTPN1 (0.43) | ALOX15MAOBKMT2APTPN1MAOA | |
| SCHEMBL11390974 | 0.79 | LMNA (0.43) | MAOBGPR35KMT2AHTT | |
| SCHEMBL11387911 | 0.77 | PTPN1 (0.50) | MAOBGPR35KMT2APTPN1MAOA | |
| SCHEMBL11394596 | 0.77 | KMT2A (0.49) | MAOBGPR35KMT2AALDH1A1 | |
| SCHEMBL11567039 | 0.77 | MAPT (0.54) | MAOBKMT2AMAOAALDH1A1HTT | |
| SCHEMBL11396850 | 0.77 | LMNA (0.62) | MAOBKMT2AMAOAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4288450-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1981-09-08 | — | — | US | claimed |
| EP-0000488-A1 | 3-Oxaloamino-4-oxo-4H-1-benzopyrane compounds, process for their preparation and their pharmaceutical use | CIBA-GEIGY AG (CH) | 1979-02-07 | — | — | EP | claimed |
| US-4288450-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1981-09-08 | — | — | US | disclosed |
| US-4216155-A | 3-GLYCOLOYLAMINO-4-OXO-4H-1-BENZOPYRAN; ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1980-08-05 | — | — | US | disclosed |
| EP-0000488-A1 | 3-Oxaloamino-4-oxo-4H-1-benzopyrane compounds, process for their preparation and their pharmaceutical use | CIBA-GEIGY AG (CH) | 1979-02-07 | — | — | EP | disclosed |