Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11563099 | 0.86 | KMT2A (0.47) | KMT2ATSHRALDH1A1HPGDPOLB | |
| SCHEMBL11394592 | 0.82 | KMT2A (0.48) | KMT2ATSHRALDH1A1HPGDPOLB | |
| SCHEMBL11391985 | 0.77 | ALOX15 (0.47) | KMT2AALDH1A1GPR35MAOB | |
| SCHEMBL11590013 | 0.77 | KMT2A (0.43) | KMT2ATSHRALDH1A1HPGDPOLB | |
| SCHEMBL11391248 | 0.75 | MAOB (0.56) | KMT2ATSHRALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11510776 | 0.75 | KMT2A (0.55) | KMT2ATSHRALDH1A1HPGDPOLB | |
| SCHEMBL11405154 | 0.74 | GPR35 (0.37) | GPR35SMN1; SMN2MAOB | |
| SCHEMBL17734459 | 0.73 | KMT2A (0.65) | KMT2ATSHRALDH1A1HPGDPOLB | |
| SCHEMBL11397533 | 0.73 | PTPN1 (0.52) | POLBGPR35LMNAMAOB | |
| SCHEMBL10967367 | 0.72 | GPR35 (0.45) | KMT2AALDH1A1MAPTGPR35SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4288450-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1981-09-08 | — | — | US | claimed |
| EP-0000488-A1 | 3-Oxaloamino-4-oxo-4H-1-benzopyrane compounds, process for their preparation and their pharmaceutical use | CIBA-GEIGY AG (CH) | 1979-02-07 | — | — | EP | claimed |
| US-4288450-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1981-09-08 | — | — | US | disclosed |
| US-4216155-A | 3-GLYCOLOYLAMINO-4-OXO-4H-1-BENZOPYRAN; ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1980-08-05 | — | — | US | disclosed |
| EP-0000488-A1 | 3-Oxaloamino-4-oxo-4H-1-benzopyrane compounds, process for their preparation and their pharmaceutical use | CIBA-GEIGY AG (CH) | 1979-02-07 | — | — | EP | disclosed |