Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11398826 | 0.83 | LMNA (0.47) | LMNAMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL11390971 | 0.83 | LMNA (0.42) | LMNAMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL11391985 | 0.79 | ALOX15 (0.47) | KMT2AMAOBGPR35HTT | |
| SCHEMBL11395264 | 0.76 | SMN1; SMN2 (0.41) | LMNAMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL11397533 | 0.75 | PTPN1 (0.52) | LMNARAB9APOLBMAOBGPR35 | |
| SCHEMBL11387911 | 0.74 | PTPN1 (0.50) | KMT2APOLBMAOBGPR35 | |
| SCHEMBL11391248 | 0.74 | MAOB (0.56) | MEN1KMT2ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL10962652 | 0.73 | PTPN1 (0.35) | LMNAMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL11400204 | 0.73 | MAOB (0.60) | MAOB | |
| Water SCHEMBL10889889 | 0.72 | PTPN1 (0.34) | LMNAMEN1KMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4288450-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1981-09-08 | — | — | US | disclosed |
| US-4216155-A | 3-GLYCOLOYLAMINO-4-OXO-4H-1-BENZOPYRAN; ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1980-08-05 | — | — | US | disclosed |
| EP-0000488-A1 | 3-Oxaloamino-4-oxo-4H-1-benzopyrane compounds, process for their preparation and their pharmaceutical use | CIBA-GEIGY AG (CH) | 1979-02-07 | — | — | EP | disclosed |