Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.33 |
| ▸ | PTPRC | P08575 | 2/20 | 0.33 |
| ▸ | PTPRB | P23467 | 2/20 | 0.33 |
| ▸ | PTPRE | P23469 | 2/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.33 |
| ▸ | PTPRF | P10586 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTPRA | P18433 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11564454 | 0.86 | PSMB5 (0.37) | GPR35NPC1RAB9AMAOBPSMB5 | |
| SCHEMBL11394596 | 0.74 | KMT2A (0.49) | GPR35MAOBSMN1; SMN2 | |
| SCHEMBL11391985 | 0.71 | ALOX15 (0.47) | GPR35PTPN1MAOB | |
| SCHEMBL11391248 | 0.69 | MAOB (0.56) | MAOBSMN1; SMN2 | |
| SCHEMBL11397533 | 0.67 | PTPN1 (0.52) | GPR35PTPN1NPC1RAB9AMAOB | |
| SCHEMBL11400204 | 0.67 | MAOB (0.60) | PTPN1MAOB | |
| SCHEMBL11567039 | 0.66 | MAPT (0.54) | NPC1RAB9AMAOBSMN1; SMN2 | |
| SCHEMBL11396850 | 0.66 | LMNA (0.62) | NPC1RAB9AMAOBSMN1; SMN2 | |
| SCHEMBL21551678 | 0.64 | GPR35 (0.59) | GPR35RAB9A | |
| SCHEMBL3723177 | 0.63 | RAB9A (0.80) | GPR35NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000488-A1 | 3-Oxaloamino-4-oxo-4H-1-benzopyrane compounds, process for their preparation and their pharmaceutical use | CIBA-GEIGY AG (CH) | 1979-02-07 | — | — | EP | claimed |
| US-4288450-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1981-09-08 | — | — | US | disclosed |
| US-4216155-A | 3-GLYCOLOYLAMINO-4-OXO-4H-1-BENZOPYRAN; ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1980-08-05 | — | — | US | disclosed |
| EP-0000488-A1 | 3-Oxaloamino-4-oxo-4H-1-benzopyrane compounds, process for their preparation and their pharmaceutical use | CIBA-GEIGY AG (CH) | 1979-02-07 | — | — | EP | disclosed |