Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11394219 | 0.88 | MPO (0.42) | SCN8ACYP1A2PTGER4SLC9A1GRM2 | |
| Dazidamine SCHEMBL286621 | 0.84 | KDM4E (0.49) | SCN8ACYP1A2PTGER4ALDH1A1SMN1; SMN2 | |
| SCHEMBL1170105 | 0.71 | CYP1A2 (0.50) | SCN8ACYP1A2PTGER4L3MBTL1CNR1 | |
| SCHEMBL1170095 | 0.71 | SCN8A (0.50) | SCN8ACYP1A2PTGER4L3MBTL1CNR1 | |
| SCHEMBL25247023 | 0.69 | SCN8A (0.49) | SCN8ACYP1A2PTGER4L3MBTL1CNR1 | |
| SCHEMBL18096451 | 0.66 | PTGER4 (0.47) | SCN8ACYP1A2PTGER4L3MBTL1CNR1 | |
| SCHEMBL4494497 | 0.64 | ALDH1A1 (0.53) | SCN8ACYP1A2PTGER4L3MBTL1ALDH1A1 | |
| SCHEMBL4485895 | 0.63 | CYP1A2 (0.49) | SCN8ACYP1A2PTGER4GRM2ALDH1A1 | |
| SCHEMBL955977 | 0.62 | ALDH1A1 (0.64) | CYP1A2ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9304768 | 0.62 | CYP19A1 (0.58) | L3MBTL1SLC9A1GRM2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4264618-A | Basic thio-indazoles | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 1981-04-28 | — | — | US | disclosed |