Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 6/20 | 0.35 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11403527 | 0.89 | AGBL2 (0.54) | AGBL2MMP2MMP9MMP12AKR1C3 | |
| SCHEMBL11402193 | 0.82 | AGBL2 (0.76) | AGBL2MMP2MMP9MMP12RXRA | |
| SCHEMBL8163677 | 0.81 | AGBL2 (0.56) | AGBL2MMP2MMP9MMP12CYP2C9 | |
| SCHEMBL11396522 | 0.81 | MMP2 (0.52) | AGBL2MMP2MMP9MMP12AKR1C3 | |
| SCHEMBL11478885 | 0.79 | CYP2C9 (0.59) | AGBL2MMP2MMP9MMP12CYP2C9 | |
| SCHEMBL11404544 | 0.79 | AGBL2 (0.52) | AGBL2MMP2MMP9MMP12CYP2C9 | |
| SCHEMBL11453265 | 0.76 | AGBL2 (0.50) | AGBL2MMP2MMP9MMP12CYP2C9 | |
| SCHEMBL11407313 | 0.76 | AGBL2 (0.62) | AGBL2MMP2MMP9MMP12RXRA | |
| SCHEMBL7031188 | 0.75 | AGBL2 (0.42) | AGBL2HPGDMAPTL3MBTL1 | |
| SCHEMBL953450 | 0.71 | NQO1 (0.54) | AKR1C3AKR1C2HPGDACACBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4282245-A | ANTIINFLAMMATORY | NIPPON CHEMIPHAR CO., LTD. (JP) | 1981-08-04 | — | — | US | disclosed |