Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 3/20 | 0.44 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 3/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CHAT | P28329 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11395104 | 1.00 | RAB9A (0.44) | RAB9APABPC1EIF4HKMT2APOLB | |
| SCHEMBL7045635 | 0.89 | RAB9A (0.51) | RAB9APABPC1EIF4HKMT2APOLB | |
| SCHEMBL11384770 | 0.89 | RAB9A (0.51) | RAB9APABPC1EIF4HKMT2APOLB | |
| SCHEMBL11386724 | 0.88 | RAB9A (0.51) | RAB9APABPC1EIF4HKMT2APOLB | |
| SCHEMBL11386719 | 0.88 | RAB9A (0.51) | RAB9APABPC1EIF4HKMT2APOLB | |
| SCHEMBL29620209 | 0.85 | RAB9A (0.57) | RAB9APABPC1EIF4HKMT2APOLB | |
| SCHEMBL1907271 | 0.85 | RAB9A (0.57) | RAB9APABPC1EIF4HKMT2APOLB | |
| SCHEMBL1980757 | 0.85 | RAB9A (0.57) | RAB9APABPC1EIF4HKMT2APOLB | |
| SCHEMBL8381110 | 0.82 | SMN1; SMN2 (0.47) | RAB9APABPC1KMT2ALMNAHTT | |
| SCHEMBL10841638 | 0.81 | RAB9A (0.47) | RAB9APABPC1EIF4HKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190091492-A1 | PHOTO-CURABLE COSMETIC COMPOSITIONS | L'OREAL (FR) | 2019-03-28 | — | — | US | disclosed |
| US-8609074-B2 | Methods for making up a keratinous substrate | L'OREAL (FR) | 2013-12-17 | — | — | US | disclosed |
| US-20130171083-A1 | PHOTO-CURABLE COSMETIC COMPOSITIONS | L'OREAL S.A. (FR) | 2013-07-04 | — | — | US | disclosed |
| US-20130167859-A1 | METHODS FOR MAKING UP A KERATINOUS SUBSTRATE | L'OREAL S.A. (FR) | 2013-07-04 | — | — | US | disclosed |
| US-4272620-A | Polyvinyl alcohol-styrylpyridinium photosensitive resins and method for manufacture thereof | AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1981-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130171083-A1 | PHOTO-CURABLE COSMETIC COMPOSITIONS | KRT18, PLOD3, LCP1 | RAB9A 3462/4885PABPC1 1217/4885EIF4H 4714/4885 |
| US-20190091492-A1 | PHOTO-CURABLE COSMETIC COMPOSITIONS | KRT18, PLOD3, LCP1 | RAB9A 3462/4885PABPC1 1217/4885EIF4H 4714/4885 |
| US-20130167859-A1 | METHODS FOR MAKING UP A KERATINOUS SUBSTRATE | KRT18, DSG1, CUTA | RAB9A 3821/4885PABPC1 1012/4885EIF4H 4717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.