Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 2/20 | 0.37 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 3/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5865884 | 0.80 | LMNA (0.44) | CA2PREPCELA1KDM4EHSD17B10 | |
| SCHEMBL9507056 | 0.80 | LMNA (0.44) | CA2PREPCELA1KDM4EHSD17B10 | |
| SCHEMBL13134484 | 0.78 | LMNA (0.42) | CA2PREPCELA1KDM4EHSD17B10 | |
| SCHEMBL14114059 | 0.77 | CA2 (0.44) | CA2KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL9168595 | 0.75 | CA2 (0.55) | CA2PREPCELA1KDM4EHSD17B10 | |
| SCHEMBL11393741 | 0.75 | THRB (0.35) | — | |
| SCHEMBL8864101 | 0.75 | CA2 (0.37) | CA2KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL23796891 | 0.71 | POLB (0.54) | CA2KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL28560018 | 0.71 | CA2 (0.43) | CA2PREPCELA1KDM4EHSD17B10 | |
| SCHEMBL20075881 | 0.71 | PREP (0.44) | CA2PREPCELA1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4268429-A | Novel flame retardant polycarbonate compositions | GENERAL ELECTRIC COMPANY (US) | 1981-05-19 | — | — | US | disclosed |
| US-4170711-A | FLAME RETARDANTS FOR POLYESTERS, POLYCARBONATES, AND POLYURETHANES | GENERAL ELECTRIC COMPANY (US) | 1979-10-09 | — | — | US | disclosed |