Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 3/20 | 0.38 |
| ▸ | CELA1 | Q9UNI1 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TOP1 | P11387 | 1/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11794835 | 0.80 | PTPN1 (0.45) | CA2PTPN1PREPCELA1KDM4E | |
| SCHEMBL20075881 | 0.78 | PREP (0.44) | CA2PREPCELA1ALDH1A1KDM4E | |
| SCHEMBL9067587 | 0.77 | PTPN1 (0.39) | CA2PTPN1ALDH1A1HSD17B10MAPK1 | |
| SCHEMBL21753716 | 0.77 | PTPN1 (0.39) | CA2PTPN1ALDH1A1HSD17B10MAPK1 | |
| SCHEMBL11396102 | 0.75 | CA2 (0.44) | CA2PTPN1PREPCELA1ALDH1A1 | |
| SCHEMBL28560018 | 0.74 | CA2 (0.43) | CA2PTPN1PREPCELA1ALDH1A1 | |
| SCHEMBL10997429 | 0.72 | PTPN1 (0.36) | CA2PTPN1 | |
| SCHEMBL10442008 | 0.72 | MAPK1 (0.50) | CA2PTPN1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL10872348 | 0.72 | ALDH1A1 (0.44) | CA2PTPN1ALDH1A1TSHR | |
| SCHEMBL29027295 | 0.72 | ELANE (0.41) | CA2PTPN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386406-B1 | Polyhaloaromatic ester flame retardants for polyolefin resins | ATOCHEM NORTH AMERICA (US) | 1995-05-17 | — | — | EP | disclosed |
| US-5086098-A | Polyhaloaromatic ester flame retardants for polyolefin resins | ATOCHEM NORTH AMERICA, INC. (US) | 1992-02-04 | — | — | US | disclosed |
| US-5043374-A | Improved flow characteristics during melt processing | ATOCHEM NORTH AMERICA, INC. (US) | 1991-08-27 | — | — | US | disclosed |
| EP-0386406-A1 | Polyhaloaromatic ester flame retardants for polyolefin resins | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1990-09-12 | — | — | EP | disclosed |
| US-4927873-A | Halophenyl ester flame retardants for polyphenylene ether resins | PENNWALT CORPORATION (US) | 1990-05-22 | — | — | US | disclosed |
| EP-0333987-A2 | Halogenated polyester flame retardants for polyphenylene ether resins | ATOCHEM NORTH AMERICA, INC. (a Pennsylvania corp.) (US) | 1989-09-27 | — | — | EP | disclosed |
| EP-0333979-A1 | Halophenyl ester flame retardants for polyphenylene ether resins | ATOCHEM NORTH AMERICA, INC. (a Pennsylvania corp.) (US) | 1989-09-27 | — | — | EP | disclosed |