SCHEMBL11396352

SCHEMBL11396352

Nc1ccc([S+]([O-])c2ccc(Br)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.62
ALOX15 P16050 3/20 0.62
MAPK1 P28482 1/20 0.62
MAPT P10636 3/20 0.48
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
CYP2A6 P11509 1/20 0.38
KDM4E B2RXH2 1/20 0.38
CA2 P00918 4/20 0.34
HTR2A P28223 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
CYP3A4 P08684 3/20 0.33
TDP1 Q9NUW8 2/20 0.33
TP53 P04637 1/20 0.33
TSHR P16473 3/20 0.32
HTR6 P50406 2/20 0.32
LMNA P02545 1/20 0.32
MPO P05164 1/20 0.32
CYP2C9 P11712 1/20 0.32
CA12 O43570 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2786319 0.87 CYP2A6 (0.50) ALDH1A1ALOX15MAPK1CYP2A6CA2
SCHEMBL310582 0.87 MEN1 (0.50) ALDH1A1ALOX15MAPK1MAPTMEN1
4-Bromoaniline SCHEMBL45481 0.79
SCHEMBL9629282 0.78 ALDH1A1 (0.41) ALDH1A1ALOX15MAPK1MAPTMEN1
SCHEMBL5549480 0.78 TSHR (0.48) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL9316559 0.78 ALDH1A1 (0.48) ALDH1A1ALOX15MAPK1MAPTMEN1
SCHEMBL9635825 0.76 CYP2A6 (0.38) ALDH1A1MAPK1MEN1KMT2ACYP2A6
SCHEMBL6912797 0.76 ACHE (0.62) ALDH1A1ALOX15MAPK1MAPTMEN1
SCHEMBL7940615 0.76 ALOX15 (0.62) ALDH1A1ALOX15MAPTMEN1KMT2A
SCHEMBL28350315 0.76 ALDH1A1 (0.62) ALDH1A1MEN1KMT2ACYP2A6KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4279637-A Herbicidal N-substituted 4-imidazolin-2-ones VELSICOL CHEMICAL CORPORATION (US) 1981-07-21 US disclosed