Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.62 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310582 | 0.87 | MEN1 (0.50) | ACHEALDH1A1TDP1MAPTMEN1 | |
| SCHEMBL235851 | 0.87 | ACHE (0.50) | ACHEALDH1A1TDP1CYP2A6CA12 | |
| SCHEMBL4401131 | 0.87 | ACHE (0.50) | ACHEALDH1A1TDP1CYP2A6CA12 | |
| SCHEMBL28288752 | 0.81 | ACHE (0.38) | ACHEALDH1A1TDP1CYP1A2CYP2A6 | |
| SCHEMBL3289160 | 0.80 | ACHE (0.42) | ACHEALDH1A1TDP1SMN1; SMN2CA1 | |
| SCHEMBL4401181 | 0.80 | ACHE (0.42) | ACHEALDH1A1TDP1SMN1; SMN2CA1 | |
| SCHEMBL25128812 | 0.80 | ALDH1A1 (0.44) | ACHEALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL8469646 | 0.79 | ACHE (1.00) | ACHETEAD4ALDH1A1TDP1MAPT | |
| SCHEMBL11887 | 0.79 | — | — | |
| SCHEMBL10505528 | 0.79 | TDP1 (0.52) | ACHEALDH1A1TDP1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6727294-B2 | RADIATION TRANSPARENT MOLDING MATERIALS | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2004-04-27 | — | — | US | disclosed |
| US-20010034419-A1 | Radiation transparent molding materials | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2001-10-25 | — | — | US | disclosed |