Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11337333 | 0.99 | TMEM97 (0.41) | TMEM97GRIN2BKCNH2PRCPOPRM1 | |
| SCHEMBL11321338 | 0.92 | TMEM97 (0.36) | TMEM97OPRM1SIGMAR1 | |
| SCHEMBL11368769 | 0.75 | OPRD1 (0.52) | TMEM97KCNH2PRCPOPRM1SIGMAR1 | |
| SCHEMBL11323060 | 0.73 | TMEM97 (0.46) | TMEM97OPRM1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL11334157 | 0.73 | OPRD1 (0.51) | TMEM97KCNH2PRCPOPRM1SIGMAR1 | |
| SCHEMBL9963303 | 0.69 | CYP2D6 (0.42) | PRCPOPRM1SIGMAR1 | |
| SCHEMBL3741530 | 0.66 | SIGMAR1 (0.35) | OPRM1SIGMAR1 | |
| SCHEMBL29190477 | 0.65 | TMEM97 (0.41) | TMEM97SIGMAR1 | |
| SCHEMBL12622887 | 0.64 | TMEM97 (0.40) | TMEM97OPRM1SIGMAR1 | |
| SCHEMBL20337468 | 0.64 | TMEM97 (0.38) | TMEM97OPRM1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4263317-A | Spiro[cyclohexane-1,1'(3'H)-isobenzofuran]s | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1981-04-21 | — | — | US | claimed |