Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | RECQL | P46063 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11390742 | 0.93 | ALDH1A1 (0.38) | ALDH1A1MAPTRECQLKDM4EMEN1 | |
| SCHEMBL11390595 | 0.91 | NOS1 (0.38) | ALDH1A1MAPTRECQLKDM4EMEN1 | |
| SCHEMBL11319704 | 0.90 | ALDH1A1 (0.42) | ALDH1A1MAPTRECQLKDM4EMEN1 | |
| SCHEMBL11365421 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MAPTRECQLKDM4EMEN1 | |
| SCHEMBL11388630 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MAPTRECQLKDM4EMEN1 | |
| SCHEMBL11395029 | 0.78 | TLR8 (0.40) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL15715957 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MAPTRECQLKDM4EMEN1 | |
| SCHEMBL11263992 | 0.76 | MAPK1 (0.48) | ALDH1A1MAPTMEN1KMT2ATHRB | |
| SCHEMBL11395049 | 0.74 | PDE10A (0.44) | ALDH1A1MAPTKDM4ESMN1; SMN2NOS1 | |
| SCHEMBL11390172 | 0.73 | ABCB11 (0.42) | ALDH1A1KDM4ETDP1NOS1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4261992-A | ANALGESIC, ANTIINFLAMMATORY, ANTIPYRETIC | RHONE POULENC INDUSTRIES (FR) | 1981-04-14 | — | — | US | disclosed |