Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 17/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.41 |
| ▸ | DNM2 | P50570 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL963512 | 0.93 | TLR8 (0.36) | TLR8TLR7KDM4ENPC1ALDH1A1 | |
| SCHEMBL17915969 | 0.89 | TLR8 (0.36) | TLR8TLR7KDM4EMEN1NPC1 | |
| SCHEMBL1450095 | 0.86 | NOS1 (0.42) | TLR8TLR7MEN1LMNAMAPT | |
| SCHEMBL11053521 | 0.86 | NOS1 (0.42) | TLR8TLR7MEN1LMNAMAPT | |
| SCHEMBL408240 | 0.86 | TLR8 (0.40) | TLR8TLR7KDM4EMEN1NPC1 | |
| Lindane SCHEMBL1672734 | 0.84 | NPC1 (0.32) | TLR8KDM4ENPC1LMNAMAPT | |
| SCHEMBL8130295 | 0.84 | SMN1; SMN2 (0.33) | TLR8TLR7KDM4ENPC1LMNA | |
| SCHEMBL3981799 | 0.81 | CA1 (0.37) | TLR8TLR7NPC1LMNAMAPK1 | |
| SCHEMBL9613719 | 0.81 | TLR8 (0.37) | TLR8TLR7KDM4EMEN1NPC1 | |
| SCHEMBL3105245 | 0.80 | CA1 (0.39) | NPC1MAPK1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0033168-A1 | Water-thinnable binders, preparation, and use in aqueous coating compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1981-08-05 | — | — | EP | disclosed |