SCHEMBL408240

SCHEMBL408240

CCCCOCNc1nc(N)nc(N)n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 12/20 0.40
TLR7 Q9NYK1 4/20 0.40
SMN1; SMN2 Q16637 3/20 0.36
GLA P06280 2/20 0.36
NPC1 O15118 2/20 0.36
MAPK1 P28482 2/20 0.36
RAB9A P51151 2/20 0.36
TP53 P04637 1/20 0.36
CDK1 P06493 1/20 0.36
CCNB1 P14635 1/20 0.36
CCNA2 P20248 1/20 0.36
CDK2 P24941 1/20 0.36
CCNA1 P78396 1/20 0.36
PIN1 Q13526 1/20 0.36
HPGD P15428 3/20 0.35
LMNA P02545 3/20 0.35
MEN1 O00255 2/20 0.35
ALDH1A1 P00352 2/20 0.35
MAPT P10636 2/20 0.35
KMT2A Q03164 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11053521 0.93 NOS1 (0.42) TLR8TLR7CDK1CCNB1CCNA2
SCHEMBL1450095 0.93 NOS1 (0.42) TLR8TLR7CDK1CCNB1CCNA2
SCHEMBL9613719 0.92 TLR8 (0.37) TLR8TLR7SMN1; SMN2GLANPC1
SCHEMBL3981799 0.89 CA1 (0.37) TLR8TLR7SMN1; SMN2GLANPC1
SCHEMBL13233288 0.87 HPGD (0.41) SMN1; SMN2GLAHPGDLMNAMEN1
Hexane SCHEMBL11397490 0.86 TLR8 (0.42) TLR8TLR7SMN1; SMN2NPC1MAPK1
SCHEMBL8379018 0.84 KCNH3 (0.35) TLR8TLR7SMN1; SMN2GLANPC1
SCHEMBL11412991 0.84 ALDH1A1 (0.36) TLR8TLR7SMN1; SMN2GLANPC1
SCHEMBL9422177 0.83 TSHR (0.42) TLR8TLR7SMN1; SMN2GLANPC1
SCHEMBL15438152 0.83 TLR8 (0.42) TLR8TLR7SMN1; SMN2NPC1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11492499-B2 Composite resin composition for steel plate for fuel tank, composite resin-coated steel plate using same, and manufacturing method therefor POSCO (KR) 2022-11-08 US claimed
CN-111240153-B Hard mask composition, hard mask and method for forming pattern 厦门恒坤新材料科技股份有限公司 2022-05-20 CN claimed
CN-111290216-B Hard mask composition, hard mask and method for forming pattern 厦门恒坤新材料科技股份有限公司 2022-05-20 CN claimed
CN-109952350-B Composite resin composition for fuel tank steel plate, composite resin coated steel plate using the same, and method for manufacturing the same POSCO公司 2021-02-19 CN claimed
CN-106687864-B Photosensitive resin composition, photosensitive element, cured product, semiconductor device, method for forming resist pattern, and method for producing circuit substrate 日立化成株式会社 2020-07-03 CN claimed
CN-111290216-A Hardmask composition, hardmask and method of forming pattern 厦门恒坤新材料科技股份有限公司 2020-06-16 CN claimed
CN-111240153-A Hardmask composition, hardmask and method of forming pattern 厦门恒坤新材料科技股份有限公司 2020-06-05 CN claimed
US-20190270894-A1 COMPOSITE RESIN COMPOSITION FOR STEEL PLATE FOR FUEL TANK, COMPOSITE RESIN-COATED STEEL PLATE USING SAME, AND MANUFACTURING METHOD THEREFOR POSCO CO., LTD (KR) 2019-09-05 US claimed
CN-105575775-B Layer structure and the method and semiconductor device for manufacturing its method, forming pattern 三星SDI株式会社 2019-08-13 CN claimed
CN-109952350-A Fuel tank steel plate composite resin composition, compound resin coated steel plates and its manufacturing method using the composition POSCO公司 2019-06-28 CN claimed
CN-1595296-A Lithographic antireflective hardmask compositions and uses thereof IBM (US) 2005-03-16 CN claimed
US-20050042538-A1 Antireflective hardmask and uses thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2005-02-24 US claimed
CN-1585097-A Antireflective hardmask and uses thereof IBM (US) 2005-02-23 CN claimed
US-20050031964-A1 Lithographic antireflective hardmask compositions and uses thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2005-02-10 US claimed
US-4857574-A SMOOTH AND GLOSSY FILM AKZO NV (NL) 1989-08-15 US claimed
EP-0172589-B1 DISPERSION OF ADDITION (CO)POLYMERS IN AN ORGANIC LIQUID AKZO N.V. (NL) 1988-11-23 EP claimed
EP-0149879-B1 HIGH SOLIDS ACRYLIC COATING COMPOSITION CONTAINING ALCOHOL SOLUBLE CELLULOSE ACETATE BUTYRATE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-08-24 EP claimed
EP-0172589-A1 Dispersion of addition (co)polymers in an organic liquid AKZO N.V. (NL) 1986-02-26 EP claimed
US-4409077-A Ultraviolet radiation curable coating composition SUMITOMO CHEMICAL CO., LTD. (JP) 1983-10-11 US claimed
US-4026857-A ALKOXYETHANOL SOLVENT, NONIONIC SURFACTANTS, CURING AGENTS, AND ACID CROSSLINKING CATALYST MOBIL OIL CORPORATION (US) 1977-05-31 US claimed