Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 3/20 | 0.47 |
| ▸ | NT5E | P21589 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 4/20 | 0.42 |
| ▸ | NSD2 | O96028 | 3/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559611 | 0.85 | NT5E (0.57) | NT5EHSD17B10ALDH1A1TDP1CASP1 | |
| SCHEMBL4650562 | 0.83 | MPL (0.50) | MPLNT5EHSD17B10TDP1CASP6 | |
| SCHEMBL7583241 | 0.82 | ALDH1A1 (0.62) | NT5EHSD17B10ALDH1A1TDP1CASP1 | |
| SCHEMBL118229 | 0.80 | PTGES (0.52) | MPLNT5EHSD17B10ALDH1A1CASP7 | |
| SCHEMBL29364155 | 0.80 | PTGES (0.52) | MPLNT5EHSD17B10ALDH1A1CASP7 | |
| SCHEMBL18274862 | 0.80 | PTGES (0.52) | MPLNT5EHSD17B10ALDH1A1CASP7 | |
| SCHEMBL31255685 | 0.80 | PTGES (0.52) | MPLNT5EHSD17B10ALDH1A1CASP7 | |
| SCHEMBL11596773 | 0.79 | CASP6 (0.46) | NT5EHSD17B10ALDH1A1TDP1CASP1 | |
| SCHEMBL1805384 | 0.79 | PTGES (0.49) | MPLNT5EHSD17B10ALDH1A1CASP6 | |
| SCHEMBL9179236 | 0.79 | PTGES (0.51) | MPLNT5EHSD17B10ALDH1A1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |
| US-4199318-A | Washfast disazo dyestuffs | TOMS RIVER CHEMICAL CORPORATION (US) | 1980-04-22 | — | — | US | disclosed |
| US-4143035-A | DISAZO DYESTUFFS HAVING AN ALKOXY GROUP ON THE FIRST AND/OR SECOND COMPONENT | TOMS RIVER CHEMICAL CORPORATION (US) | 1979-03-06 | — | — | US | disclosed |