SCHEMBL11399402

SCHEMBL11399402

CCc1ccc(N)c(S)c1Cl

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTRC Q99895 1/20 0.35
POLB P06746 3/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.33
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
THRB P10828 1/20 0.32
APEX1 P27695 1/20 0.32
RECQL P46063 1/20 0.32
RAB9A P51151 1/20 0.32
BLM P54132 1/20 0.32
KMT2A Q03164 1/20 0.32
MCL1 Q07820 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HTR1A P08908 2/20 0.32
DRD2 P14416 2/20 0.32
DRD4 P21917 2/20 0.32
HTR2A P28223 2/20 0.32
HTR2C P28335 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21852155 0.80 POLB (0.40) CTRCPOLBALDH1A1MAPTMEN1
SCHEMBL31569145 0.78 CTRC (0.38) CTRCPOLBALDH1A1MAPTMEN1
SCHEMBL11800708 0.77 CTRC (0.36) CTRCPOLBALDH1A1MAPTMEN1
SCHEMBL11725420 0.77 ESR1 (0.38) CTRCMAPTMEN1BLMKMT2A
SCHEMBL13862899 0.75 CTRC (0.35) CTRCPOLBALDH1A1MAPTMEN1
SCHEMBL11569486 0.75 GABRA1 (0.46) POLBALDH1A1MAPTHTT
SCHEMBL12658946 0.74 CTRC (0.48) CTRCHTR1ADRD2DRD4HTR2A
SCHEMBL25457914 0.72 ALDH1A1 (0.38) CTRCPOLBALDH1A1MAPTMEN1
SCHEMBL20640459 0.72 POLB (0.38) CTRCPOLBALDH1A1MAPTMEN1
SCHEMBL2215938 0.71 GABRA1 (0.46) CTRCPOLBALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0010249-A2 Herbicidal agents, process for their preparation and their use in combating weeds BAYER AG (DE) 1980-04-30 EP disclosed
EP-0010250-A2 Use of Sulfonanilides in inhibition of plant growth BAYER AG (DE) 1980-04-30 EP disclosed