Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 14/20 | 0.44 |
| ▸ | DRD4 | P21917 | 5/20 | 0.42 |
| ▸ | DRD3 | P35462 | 5/20 | 0.40 |
| ▸ | PRCP | P42785 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11331661 | 0.99 | DRD2 (0.44) | DRD2DRD4DRD3PRCPHTR1A | |
| SCHEMBL11391165 | 0.97 | DRD2 (0.40) | DRD2DRD4DRD3HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL11326699 | 0.96 | DRD2 (0.39) | DRD2DRD4HTR1AHTR2AHTR2C | |
| SCHEMBL11369641 | 0.94 | DRD2 (0.43) | DRD2DRD4DRD3HTR1AHTR2A | |
| Bromide SCHEMBL11337378 | 0.93 | DRD2 (0.43) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL11377955 | 0.88 | DRD2 (0.38) | DRD2DRD4DRD3HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL11318513 | 0.87 | L3MBTL1 (0.38) | DRD2DRD4DRD3HTR1AHTR2A | |
| Oxalic Acid SCHEMBL11322198 | 0.80 | DRD2 (0.39) | DRD2DRD4HTR1AHTR2AHTR2C | |
| Oxalic Acid SCHEMBL11326300 | 0.79 | AGTR2 (0.40) | OPRM1GRIN2BTMEM97SIGMAR1 | |
| SCHEMBL11323073 | 0.76 | HTR2A (0.42) | PRCPHTR2AHTR2CHTR2BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4263317-A | Spiro[cyclohexane-1,1'(3'H)-isobenzofuran]s | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1981-04-21 | — | — | US | claimed |