Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.34 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PGD | P52209 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18039277 | 0.90 | MMP1 (0.45) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL5718402 | 0.90 | MMP1 (0.45) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL28281334 | 0.88 | MMP1 (0.43) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL3979990 | 0.82 | PGD (0.42) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL13312893 | 0.81 | TSHR (0.40) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL26940409 | 0.78 | MMP1 (0.48) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL9628984 | 0.78 | MMP1 (0.48) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL16837638 | 0.77 | MMP1 (0.40) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL10593783 | 0.76 | SLC1A3 (0.43) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL4368789 | 0.75 | TSHR (0.38) | MMP1MMP2MMP3MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55092343-A | — | — | None | — | — | JP | disclosed |
| US-8546388-B2 | Heterocyclic TRPV1 receptor ligands | PURDUE PHARMA L.P. (US) | 2013-10-01 | — | — | US | disclosed |
| US-20100137306-A1 | HETEROCYCLIC TRPV1 RECEPTOR LIGANDS | PURDUE PHARMA L.P. | 2010-06-03 | — | — | US | disclosed |
| JP-S5592343-A | PREPARATION OF OPTICALLY ACTIVE SUBSTITUTED ISOVALERIC ACID | KATSUTA YOSHIO | 1980-07-12 | — | — | JP | disclosed |
| US-4201787-A | Isovaleric acid ester derivatives, and insecticides containing said derivatives | DAINIPPON JOCHUGIKU KABUSHIKI KAISHA (JP) | 1980-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137306-A1 | HETEROCYCLIC TRPV1 RECEPTOR LIGANDS | TRPV1, TRPA1, TRPV2 | MMP1 3152/4885MMP2 4374/4885MMP3 4621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.