Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7317623 | 0.82 | TP53 (0.38) | MAPTPRKCAGSK3BCDK2ALDH1A1 | |
| SCHEMBL9869210 | 0.80 | KIF11 (0.41) | GSK3BALDH1A1 | |
| SCHEMBL9796410 | 0.74 | TRPA1 (0.36) | MAPTRXFP1PRKCAGSK3BCDK2 | |
| SCHEMBL11388955 | 0.73 | MAPT (0.40) | MAPTRXFP1ALDH1A1TP53 | |
| SCHEMBL5985272 | 0.69 | TP53 (0.43) | PRKCAGSK3BCDK2ALDH1A1IMPDH2 | |
| SCHEMBL17443787 | 0.68 | BRD4 (0.44) | ALDH1A1 | |
| SCHEMBL10619004 | 0.67 | ALDH1A1 (0.36) | MAPTRXFP1PRKCAGSK3BALDH1A1 | |
| SCHEMBL11060070 | 0.67 | SCN9A (0.37) | MAPTPRKCAGSK3BCDK2ALDH1A1 | |
| SCHEMBL13806311 | 0.66 | TDP1 (0.41) | PRKCAGSK3BALDH1A1IMPDH2TP53 | |
| SCHEMBL12410857 | 0.66 | ALDH1A1 (0.37) | MAPTPRKCAGSK3BCDK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4302460-A | 4-Quinolinones having antihypertensive activity | THE BOOTS COMPANY LIMITED (GB) | 1981-11-24 | — | — | US | disclosed |