Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAT2A | P31153 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ACLY | P53396 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAP2 | P11137 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KRAS | P01116 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11461065 | 0.84 | HTT (0.46) | KMT2AHTTL3MBTL1MEN1SMN1; SMN2 | |
| SCHEMBL11404527 | 0.75 | ACLY (0.44) | KMT2AMAT2AKDM4EACLYMAPT | |
| Hydrochloric Acid SCHEMBL11452185 | 0.74 | MAT2A (0.50) | KMT2AMAT2AKDM4EACLYMAPT | |
| Hydrochloric Acid SCHEMBL11452275 | 0.74 | MAT2A (0.50) | KMT2AMAT2AKDM4EACLYMAPT | |
| SCHEMBL27870399 | 0.71 | ALDH1A1 (0.47) | KMT2AMAT2AKDM4EACLYMAPT | |
| Ethyl Acetate SCHEMBL27410326 | 0.71 | KMT2A (0.51) | KMT2AKDM4EACLYMAPTHPGD | |
| SCHEMBL11711011 | 0.70 | KRAS (0.51) | KMT2AKDM4EACLYMAPTL3MBTL1 | |
| SCHEMBL11403262 | 0.70 | MAT2A (0.42) | KMT2AMAT2AKDM4EACLYMAPT | |
| SCHEMBL11454351 | 0.68 | MAT2A (0.44) | MAT2A | |
| SCHEMBL24095575 | 0.67 | HSD17B10 (0.69) | KMT2AMAT2AKDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0042054-A1 | 1-Amino-3-phenyl indoles, their salts and medicaments containing them | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1981-12-23 | — | — | EP | disclosed |