Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CPT2 | P23786 | 1/20 | 0.40 |
| ▸ | CPT1A | P50416 | 1/20 | 0.40 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11401724 | 0.84 | KMT2A (0.44) | HTTL3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11464649 | 0.80 | HTR6 (0.46) | HTTHTR6PTGER1HSD17B10L3MBTL1 | |
| SCHEMBL8481500 | 0.74 | HTT (0.75) | HTTHTR6PTGER1HSD17B10BRD4 | |
| Binedaline SCHEMBL49440 | 0.73 | L3MBTL1 (0.42) | HTR6HSD17B10L3MBTL1BRD4MEN1 | |
| Binedaline SCHEMBL29393236 | 0.73 | L3MBTL1 (0.42) | HTR6HSD17B10L3MBTL1BRD4MEN1 | |
| Binedaline SCHEMBL5957158 | 0.72 | L3MBTL1 (0.41) | HTTHTR6HSD17B10L3MBTL1BRD4 | |
| SCHEMBL10973389 | 0.71 | HTR6 (0.48) | HTTHTR6PTGER1HSD17B10L3MBTL1 | |
| SCHEMBL11452382 | 0.71 | L3MBTL1 (0.40) | HTR6L3MBTL1 | |
| SCHEMBL7582044 | 0.70 | HTT (0.56) | HTTHTR6PTGER1HSD17B10L3MBTL1 | |
| SCHEMBL11452293 | 0.70 | L3MBTL1 (0.39) | HTR6HSD17B10L3MBTL1BRD4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204998-A | N-Amino indole derivatives having pharmacological activity | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1980-05-27 | — | — | US | disclosed |