Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 4/20 | 0.50 |
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11402034 | 0.85 | POLQ (0.52) | POLQTACR1ALDH1A1POLBALOX15 | |
| SCHEMBL14955365 | 0.84 | POLQ (0.51) | POLQTACR1ALDH1A1POLBALOX15 | |
| SCHEMBL9357893 | 0.81 | LMNA (0.57) | POLQTACR1LTB4R2ALDH1A1ALOX15 | |
| SCHEMBL28746573 | 0.80 | LTB4R2 (0.47) | LTB4R2ALDH1A1TP53 | |
| SCHEMBL28141847 | 0.80 | TP53 (0.50) | POLQTACR1ALDH1A1POLBHSD17B1 | |
| SCHEMBL11174926 | 0.80 | TACR1 (0.50) | POLQTACR1ALDH1A1POLBHSD17B1 | |
| SCHEMBL23222221 | 0.78 | ALDH1A1 (0.51) | ALDH1A1POLBHSD17B1HSD17B2TP53 | |
| SCHEMBL8601016 | 0.78 | TP53 (0.49) | POLQTACR1ALDH1A1POLBHSD17B1 | |
| SCHEMBL10943479 | 0.78 | TP53 (0.49) | POLQTACR1ALDH1A1POLBHSD17B1 | |
| SCHEMBL15979067 | 0.77 | HTR3E (0.53) | POLQLTB4R2ALDH1A1HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539121-A | A novel, photo-promoted process for the preparation of sulfonates and sulfonamides from sulfonyl chlorides | 天津师范大学 | 2022-05-27 | — | — | CN | disclosed |
| US-20110021525-A1 | P70S6 Kinase Modulators and Method of Use | EXELIXIS, INC. (US) | 2011-01-27 | — | — | US | disclosed |
| US-7816353-B2 | P70S6 kinase modulators and method of use | EXELIXIS, INC. (US) | 2010-10-19 | — | — | US | disclosed |
| US-20070208020-A1 | P70S6 Kinase Modulators And Method Of Use | EXELIXIS, INC. | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021525-A1 | P70S6 Kinase Modulators and Method of Use | EEF2K, RPS6KA3, MTOR | POLQ 2689/4885TACR1 2751/4885LTB4R2 3086/4885 |
| US-20070208020-A1 | P70S6 Kinase Modulators And Method Of Use | EEF2K, RPS6KA3, MTOR | POLQ 2689/4885TACR1 2751/4885LTB4R2 3086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.