Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.56 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MDH2 | P40926 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11273297 | 0.91 | GABRA1 (0.65) | GABRA1GABRB2GABRB1GABRA3ALDH1A1 | |
| SCHEMBL11246680 | 0.84 | MDH2 (0.68) | ALDH1A1HPGDMDH2SMN1; SMN2MEN1 | |
| SCHEMBL2977304 | 0.84 | GABRA1 (0.62) | GABRA1GABRB2GABRB1GABRA3ALDH1A1 | |
| SCHEMBL4176704 | 0.82 | MDH2 (0.76) | GABRA1GABRB2GABRB1GABRA3ALDH1A1 | |
| SCHEMBL28287752 | 0.80 | GABRA1 (0.66) | GABRA1GABRB2GABRB1GABRA3ALDH1A1 | |
| SCHEMBL1285395 | 0.79 | GABRA1 (0.60) | GABRA1GABRB2GABRB1GABRA3ALDH1A1 | |
| SCHEMBL30906938 | 0.78 | GABRA1 (0.63) | GABRA1GABRB2GABRB1GABRA3ALDH1A1 | |
| SCHEMBL30906939 | 0.78 | GABRA1 (0.63) | GABRA1GABRB2GABRB1GABRA3ALDH1A1 | |
| SCHEMBL1430520 | 0.78 | GABRA1 (0.63) | GABRA1GABRB2GABRB1GABRA3ALDH1A1 | |
| SCHEMBL1430217 | 0.78 | GABRA1 (0.81) | GABRA1GABRB2GABRB1GABRA3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4289777-A | Quinolonecarboxylic acid derivatives and pharmaceutical preparations thereof for treatment of an allergic disease of the respiratory tract | SCHERING, AKTIENGESELLSCHAFT (DE) | 1981-09-15 | — | — | US | disclosed |