Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.55 |
| ▸ | G6PD | P11413 | 2/20 | 0.53 |
| ▸ | FBP1 | P09467 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11405244 | 0.91 | ALDH1A1 (0.55) | ALDH1A1MAPTALOX15TSHRRECQL | |
| SCHEMBL11404276 | 0.89 | ALDH1A1 (0.62) | ALDH1A1MAPTALOX15TSHRRECQL | |
| SCHEMBL11420882 | 0.89 | ALDH1A1 (0.68) | ALDH1A1MAPTALOX15TSHRRECQL | |
| SCHEMBL16634831 | 0.88 | ALDH1A1 (0.76) | ALDH1A1MAPTALOX15TSHRRECQL | |
| SCHEMBL16634847 | 0.88 | ALDH1A1 (0.76) | ALDH1A1MAPTALOX15TSHRRECQL | |
| SCHEMBL11404001 | 0.84 | ALDH1A1 (0.49) | ALDH1A1MAPTALOX15TSHRRECQL | |
| SCHEMBL11408521 | 0.84 | NFE2L2 (0.57) | ALDH1A1MAPTALOX15TSHRRECQL | |
| SCHEMBL11410261 | 0.83 | ACHE (0.50) | ALDH1A1MAPTALOX15TSHRRECQL | |
| SCHEMBL11410435 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPTALOX15TSHRRECQL | |
| SCHEMBL264278 | 0.82 | ALDH1A1 (0.73) | ALDH1A1MAPTALOX15TSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4224340-A | Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds | WILLIAM H. RORER, INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4214003-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4197314-A | WITH A DIPHENYL NITRONE | WILLIAM H. RORER, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153722-A | ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE | WILLIAM H. RORER, INC. (US) | 1979-05-08 | — | — | US | disclosed |