Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18231699 | 0.83 | HCAR3 (0.42) | HIF1AEPAS1TDP1TP53SMN1; SMN2 | |
| SCHEMBL10111220 | 0.83 | ALDH1A1 (0.38) | TDP1TP53SMN1; SMN2HTTKMT2A | |
| SCHEMBL5539545 | 0.81 | HIF1A (0.40) | HIF1AEPAS1TDP1TP53SMN1; SMN2 | |
| SCHEMBL9258889 | 0.80 | ALDH1A1 (0.42) | TDP1TP53SMN1; SMN2MEN1KMT2A | |
| SCHEMBL27706443 | 0.79 | PYCR1 (0.40) | HTTMEN1KMT2ACYP3A4PYCR1 | |
| SCHEMBL25794046 | 0.79 | CRHR1 (0.35) | CRHR1 | |
| SCHEMBL15872033 | 0.79 | SMN1; SMN2 (0.46) | HIF1AEPAS1TDP1TP53SMN1; SMN2 | |
| Lithium Ion SCHEMBL19732788 | 0.78 | ALDH1A1 (0.41) | TDP1TP53SMN1; SMN2HTTMEN1 | |
| SCHEMBL15541232 | 0.78 | ALDH1A1 (0.44) | HIF1AEPAS1TDP1TP53SMN1; SMN2 | |
| SCHEMBL20684154 | 0.78 | SLC6A2 (0.39) | HIF1AEPAS1TDP1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632443-B1 | ANTI-TUMOR EFFECT POTENTIATOR USING A BIPHENYL COMPOUND | TAIHO PHARMACEUTICAL CO LTD (JP) | 2023-06-07 | — | — | EP | disclosed |
| US-4251667-A | Process for the preparation of aromatic urethanes | ATLANTIC RICHFIELD COMPANY (US) | 1981-02-17 | — | — | US | disclosed |
| US-4222959-A | Process for the preparation of aromatic formamides | ATLANTIC RICHFIELD COMPANY (US) | 1980-09-16 | — | — | US | disclosed |
| US-4097524-A | Process for the preparation of formamides | ATLANTIC RICHFIELD COMPANY (US) | 1978-06-27 | — | — | US | disclosed |