Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11405183 | 0.84 | MAP2K2 (0.43) | LMNAKMT2AMEN1NFE2L2HPGD | |
| SCHEMBL9228325 | 0.79 | LMNA (0.44) | LMNAALDH1A1TSHRRAB9AMAPT | |
| SCHEMBL25043218 | 0.79 | LMNA (0.44) | LMNAALDH1A1TSHRRAB9AMAPT | |
| SCHEMBL3650326 | 0.77 | ALDH1A1 (0.42) | LMNAALDH1A1TSHRRAB9AMAPT | |
| SCHEMBL30950200 | 0.77 | ALDH1A1 (0.42) | LMNAALDH1A1TSHRRAB9AMAPT | |
| SCHEMBL12811744 | 0.77 | RAB9A (0.60) | LMNAALDH1A1TSHRRAB9AMAPT | |
| SCHEMBL13446748 | 0.77 | RAB9A (0.45) | LMNAALDH1A1TSHRRAB9AMAPT | |
| SCHEMBL3899333 | 0.76 | CA3 (0.48) | LMNAALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL10882869 | 0.76 | GAA (0.55) | LMNAALDH1A1TSHRRAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL4587796 | 0.76 | ALDH1A1 (0.41) | LMNAALDH1A1TSHRRAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4224340-A | Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds | WILLIAM H. RORER, INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4214003-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4197314-A | WITH A DIPHENYL NITRONE | WILLIAM H. RORER, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153722-A | ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE | WILLIAM H. RORER, INC. (US) | 1979-05-08 | — | — | US | disclosed |