Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9232081 | 0.79 | PDK2 (0.37) | RAB9ANPC1SMN1; SMN2PDK2PDK1 | |
| SCHEMBL3533485 | 0.79 | ALDH1A1 (0.48) | RAB9ANPC1SMN1; SMN2PDK2PDK1 | |
| Hydrochloric Acid SCHEMBL4083043 | 0.78 | ALDH1A1 (0.52) | RAB9ANPC1SMN1; SMN2PDK2PDK1 | |
| SCHEMBL11406409 | 0.78 | KDR (0.39) | SMN1; SMN2PDK2PDK1PDK3PDK4 | |
| SCHEMBL1541726 | 0.77 | TRPA1 (0.40) | PDK2P2RX7ALDH1A1TRPA1CES2 | |
| SCHEMBL12498327 | 0.75 | TRPA1 (0.40) | SMN1; SMN2PDK2PDK1PDK3PDK4 | |
| SCHEMBL28004081 | 0.73 | CES2 (0.37) | PDK2P2RX7MEN1KMT2AALDH1A1 | |
| SCHEMBL5703062 | 0.72 | — | — | |
| SCHEMBL6054954 | 0.72 | RAB9A (0.60) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4120536 | 0.71 | ALDH1A1 (0.38) | RAB9ANPC1SMN1; SMN2PDK2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4224340-A | Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds | WILLIAM H. RORER, INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4214003-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4197314-A | WITH A DIPHENYL NITRONE | WILLIAM H. RORER, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153722-A | ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE | WILLIAM H. RORER, INC. (US) | 1979-05-08 | — | — | US | disclosed |