SCHEMBL11405331

SCHEMBL11405331

CON(c1ccccc1)S(=O)(=O)c1cc[c]cc1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.51
CA12 O43570 1/20 0.40
CA9 Q16790 1/20 0.40
PKM P14618 1/20 0.40
ESR1 P03372 4/20 0.38
PGR P06401 1/20 0.37
KMT2A Q03164 2/20 0.37
LMNA P02545 1/20 0.37
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
HSD17B10 Q99714 1/20 0.36
APOBEC3G Q9HC16 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11405054 0.83 ALDH1A1 (0.47) ALDH1A1CA12CA9PKMESR1
SCHEMBL6792747 0.81 PKM (0.58) ALDH1A1CA12CA9PKMESR1
SCHEMBL2797281 0.78 ALDH1A1 (0.49) ALDH1A1CA12CA9PKMESR1
SCHEMBL693817 0.77 CA12 (0.66) CA12CA9PGRKMT2ALMNA
SCHEMBL6678557 0.77 PKM (0.66) ALDH1A1CA12CA9PKMESR1
SCHEMBL11405313 0.77 ALDH1A1 (0.40) ALDH1A1CA12CA9PKMESR1
SCHEMBL5459206 0.74 PTGES (0.46) ALDH1A1ESR1LMNATSHRMAPK1
SCHEMBL11404892 0.74 PKM (0.43) ALDH1A1CA12CA9PKMESR1
SCHEMBL11404947 0.73 ESR1 (0.67) ALDH1A1ESR1KMT2ALMNATSHR
SCHEMBL9954268 0.73 KEAP1 (0.48) ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4202814-A AZO DYES GIVING FAST RED COLOR CIBA-GEIGY CORPORATION (US) 1980-05-13 US disclosed