Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11407867 | 0.98 | PPARA (0.41) | PPARAPTGS2CYP3A4ALOX5PTGS1 | |
| SCHEMBL11398250 | 0.95 | PPARA (0.34) | PPARACYP3A4TYRALOX5 | |
| SCHEMBL2911934 | 0.83 | L3MBTL1 (0.47) | PPARA | |
| SCHEMBL3923663 | 0.72 | MAPT (0.41) | PPARAPTGS2CYP3A4TYRALOX15 | |
| SCHEMBL9769164 | 0.71 | MAPT (0.44) | PPARAPTGS2CYP3A4ELANE | |
| SCHEMBL18977711 | 0.70 | SPHK2 (0.37) | ALOX5 | |
| SCHEMBL9769157 | 0.69 | MAPT (0.37) | PPARAPTGS2CYP3A4TYRALOX5 | |
| SCHEMBL4676588 | 0.69 | THRA (0.34) | PPARAEPHX2 | |
| SCHEMBL4676591 | 0.69 | THRA (0.34) | PPARAEPHX2 | |
| SCHEMBL11397141 | 0.69 | DAO (0.43) | PTGS2CYP3A4TYRALOX5ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4282246-A | Antidiabetic furancarboxylic and thiphenecarboxylic acids | PFIZER INC. (US) | 1981-08-04 | — | — | US | disclosed |