Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2913260 | 0.83 | DAO (0.66) | DAOGAALMNAGPR35RAB9A | |
| SCHEMBL11407858 | 0.81 | DAO (0.64) | DAOGPR35ALDH1A1MEN1KMT2A | |
| SCHEMBL11748148 | 0.81 | GAA (0.44) | DAOGAALMNAHTTTDP1 | |
| SCHEMBL11398245 | 0.77 | DAO (0.68) | DAOGAALMNAHTTTDP1 | |
| SCHEMBL28446589 | 0.74 | THRA (0.55) | DAOGAALMNAGPR35RAB9A | |
| SCHEMBL17707867 | 0.72 | LTB4R (0.45) | LMNATP53ALDH1A1PTGS2CYP3A4 | |
| SCHEMBL29164246 | 0.72 | GPR84 (0.40) | GAAGPR35RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21129395 | 0.72 | ALDH1A1 (0.37) | GAAGPR35ALDH1A1MEN1KMT2A | |
| SCHEMBL18977810 | 0.71 | ALDH1A1 (0.38) | DAOGAALMNATDP1RAB9A | |
| SCHEMBL19304386 | 0.71 | PTGS2 (0.38) | GAAGPR35ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4282246-A | Antidiabetic furancarboxylic and thiphenecarboxylic acids | PFIZER INC. (US) | 1981-08-04 | — | — | US | disclosed |